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KMID : 0605720080140010094
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Journal of the Korean Society of Biological Therapies in Psychiatry
2008 Volume.14 No. 1 p.94 ~ p.100
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Dissociation, Childhood Abuse, and Clinical Symptomatology in Schizophrenia
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Lee Gyeong-Woo
Bae Hwal-Lip
Kim Yang-Suk
Park June-Sung
Kim Dae-Ho
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Abstract
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Objectives : Studies consistently find high prevalence of early sexual or physical abuse among the schizophrenic population suggesting a possible linkage between psychological trauma and schizophrenia. This study sought for clinical correlates of dissociative symptoms in schizophrenia concerning childhood abuse and a variety of symptoms.
Methods : Sixty-one inpatients with schizophrenia completed Dissociative Experiences Scale(DES), Symptom Checklist-90-Revised(SCL-90-R), Positive and Negative Syndrome Scale(PANSS), and a semistructured interview on abuse history.
Results : The Global Severity Index(GSI) of SCL-90-R, positive symptom, chlorpromazine equivalent, and childhood abuse were significantly correlated with DES scores. However, multiple regression analysis yielded GSI and positive symptom accounting 57% of variance for DES scores.
Conclusion : This finding suggests that the symptoms of dissociation in schizophrenia are rather associated with severity of general symptomatology and positive symptoms than history of childhood abuse. Some portion of schizophrenic population with high scores on DES need to be further investigated for their characteristics and pathophysiology.
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KEYWORD
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Schizophrenia, Dissociation, Child abuse, Trauma, Positive symptoms
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